出版日期：2015-05-06 00:00:00

著者：Don, Trong-ming

著錄名稱、卷期、頁數：Journal of Polymer Science Part A: Polymer Chemistry 53(18),　p.2152-2162

摘要：Crosslinking magnetic thermoresponsive composite (MTC) fiber mats were fabricated by electrospinning process and followed by UV curing. Thermoresponsive poly-(N-isopropylacrylamide) (PNIPAAm) and magnetic Fe3O4 were firstly synthesized by redox-initiated polymerization and co-precipitation, respectively. A crosslinking agent (dipentaerythritol hexylacrylate) and photoinitiator for providing crosslinking ability were then mixed with PNIPAAm and Fe3O4 in ethanol as the electrospinning solution. After electrospinning and subsequent UV irradiation, the MTC fiber mats were thus obtained. Thermoresponsivity of the MTC fibers was measured by both DSC and swelling test. MTC fiber mat exhibited better water-absorption capability and thermoresponsivity than corresponding film. Morphological analysis was observed by SEM and TEM, and the magnetic property was measured by SQUID. The thermoresponsive magnetic behavior of MTC fiber mat in water was observed under various temperatures and magnetic fields. Vitamin B12 used as a model drug was loaded in the MTC fiber mats and the drug-release behavior was then studied.

關鍵字：composite;crosslinking;drug delivery systems;electrospinning fibers;fibers;thermoresponsive polymer

語言：en_US

ISSN：1099-0518

期刊性質：國外

收錄於：SCI EI

通訊作者：Wen-Yen Chiu

審稿制度：是

國別：USA

出版型式：電子版,紙本