出版日期：2023-01-01 00:00:00

著者：Wei‐Chi Lai; Wen‐Bin Liau; Ling‐Yueh Yang

著錄名稱、卷期、頁數：Polymers for Advanced Technologies 34(1), p.398-404

摘要：In this study, porous poly(L-lactic acid) (PLLA) films are prepared via a facile and low-cost approach using poly(ethylene glycol) (PEG) and solution casting. In contrast to most studies, the PEG/PLLA samples are further processed under different crystallization conditions (i.e., different PLLA crystallization temperatures) before PEG removal. As the PEG is extracted via solvent at higher PLLA crystallization temperatures, the resultant PLLA samples have larger pores. Interconnected fibrillar-shaped pores are found in all systems, and the fibrillar-porous structure width is ~150 nm–1.2 μm, as observed via scanning electron microscopy. These pore sizes can be tuned by adjusting the blend composition and crystallization temperature. In addition, PEG/PLLA blends are subjected to hydrolytic degradation analysis according to their crystallization conditions. Higher PLLA crystallization temperature yields higher PLLA crystallinity and larger pores, as well as reduced surface interaction with water. Therefore, the PLLA degradation rate is decreased. The developed PLLA films have potential applications in drug delivery and tissue engineering.

語言：en

ISSN：1042-7147;1099-1581

期刊性質：國外

收錄於：SCI

審稿制度：否

國別：GBR

出版型式：電子版