出版日期：2023-07-27 00:00:00

著者：Chii-Dong Ho; Jr-Wei Tu; Yih-Hang Chen; Thiam Leng Chew

著錄名稱、卷期、頁數：Membranes 13(8), p.702-726

摘要：This research theoretically and experimentally develops a hollow-fiber dialysis module coupled with ultrafiltration operations by introducing a trans-membrane pressure during the membrane dialysis process, which can be applied to the waste metabolic end products in the human body for improving the dialysis efficiency. The solutes were transported by both diffusion and convection from the concentration driving-force gradient between retentate and dialysate phases across the membrane, compared to the traditional dialysis processes by diffusion only. A two-dimensional modeling of such a dialysis-and-ultrafiltration system in the hollow-fiber dialysis module was formulated and solved using the stream function coupled with the perturbation method to obtain the velocity distributions of retentate and dialysate phases, respectively. The purpose of the present work is to investigate the effect of ultrafiltration on the dialysis rate in the hollow-fiber dialyzer with ultrafiltration operations. A highest level of dialysis rate improvement up to about seven times (say 674.65% under 𝑉𝑎=20 mL/min) was found in the module with ultrafiltration rate 𝑉𝑤=10 mL/min and membrane sieving coefficient 𝜃=1 , compared to that in the system without operating ultrafiltration. Considerable dialysis rate improvements on mass transfer were obtained by implementing a hollow-fiber dialysis-and-ultrafiltration system, instead of using the hollow-fiber dialyzer without ultrafiltration operation. The experimental runs were carried out under the same operating conditions for the hollow-fiber dialyzers of the two experimental runs with and without ultrafiltration operations for comparisons. A very reasonable prediction by the proposed mathematical model was observed.

關鍵字：hollow-fiber module;dialysis;ultrafiltration;device performance;dialysis-and-ultrafiltration system

語言：en

ISSN：2077-0375

期刊性質：國外

收錄於：SCI EI

通訊作者：Chii-Dong Ho

審稿制度：是

國別：CHE

出版型式：電子版